Document Detail


Detection and removal of pathogenic biofilms on medical implant surfaces.
MedLine Citation:
PMID:  16282672     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Advances in sensor technology have had a significant impact in medical research and practice in the last decade. However, within the hospital environment problems still exist where the application of sensing technology could provide the solution. The presence of antibiotic resistant bacteria within hospitals and the risk of serious infection that they pose is a cause for concern. This paper describes a research project that has recently started at the University of Ulster investigating the potential of "Sense and Destroy" tactics to reduce the spread of medical device related infections. It is proposed that Electrical Impedance Spectroscopy (EIS) probes implanted within a catheter may be used to detect subclinical biofilm formation. Furthermore, if the presence of a biofilm is detected, activation of a photocatalytic coating on the catheter wall may be used to inactivate the responsible microorganisms.
Authors:
Patrick Dunlop; Louise Oliver; Tony Byrne; Eric McAdams
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Studies in health technology and informatics     Volume:  117     ISSN:  0926-9630     ISO Abbreviation:  Stud Health Technol Inform     Publication Date:  2005  
Date Detail:
Created Date:  2005-11-11     Completed Date:  2006-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9214582     Medline TA:  Stud Health Technol Inform     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  T    
Affiliation:
Northern Ireland Bio-Engineering Centre, University of Ulster at Jordanstown, UK. psm.dunlop@ulster.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Biofilms*
Biosensing Techniques / methods*
Cross Infection / diagnosis,  therapy
Drug Resistance, Multiple, Bacterial
Electric Impedance / diagnostic use
Equipment and Supplies / microbiology*
Humans
Photochemotherapy / methods*
Spectrum Analysis / methods
Titanium / therapeutic use*
Chemical
Reg. No./Substance:
13463-67-7/titanium dioxide; 7440-32-6/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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