| Detection of regional pulmonary perfusion deficit of the occluded lung using arterial spin labeling in magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 10713940 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Detection of regional perfusion deficit in the lung has been demonstrated using an arterial spin labeling technique called flow-sensitive alternating inversion recovery with an extra radiofrequency pulse (FAIRER). A pulmonary artery was occluded using a nondetachable balloon catheter to simulate an acute pulmonary embolism in 3 of 10 rabbits. Inflating the balloon occludes the artery, and deflating the balloon allows for reperfusion. Perfusion imaging was performed pre-occlusion, during occlusion, and after reperfusion. Signal enhancement due to perfusion of the pulmonary parenchyma was observed in the perfusion images with negligible artifacts. The perfusion deficit of the pulmonary parenchyma was detected distal to the site of occlusion in all three rabbits. Return of the pulmonary parenchymal perfusion was observed after reperfusion. Magnetic resonance imaging using FAIRER can detect signal loss due to absence of perfusion caused by pulmonary embolism. |
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Authors:
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V M Mai; K D Hagspiel; T Altes; A R Goode; M B Williams; S S Berr |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 11 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2000 Feb |
Date Detail:
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Created Date: 2000-04-05 Completed Date: 2000-04-05 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 97-102 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Lung / blood supply* Magnetic Resonance Imaging / methods* Pulmonary Circulation / physiology Pulmonary Embolism / diagnosis* Rabbits |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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