| Detection of recurrent ovarian cancer at MRI: comparison with integrated PET/CT. | |
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MedLine Citation:
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PMID: 18043348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the diagnostic performances of magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) for the detection of recurrent ovarian tumor. METHODS: Thirty-six patients who underwent primary cytoreductive surgery for ovarian carcinoma received both MRI and PET/CT for the evaluation of ovarian tumor recurrence. Recurrent ovarian tumors in abdomen and pelvis were classified based on site as follows: (1) local pelvic recurrence, (2) peritoneal lesion, (3) lymph nodal metastasis, and (4) distant metastasis. Patient-based and lesion-based analyses were retrospectively performed with the aim of detecting tumor recurrence. For the detection of recurrent ovarian tumors, we compared patient-based and lesion-based diagnostic accuracies of these 2 modalities using the McNemar test. RESULTS: Histopathologic, clinical, and radiological follow-up findings revealed recurrent ovarian tumors in 35 sites of 22 patients. These 35 sites consisted of local pelvic recurrence (n = 15), peritoneal lesions (n = 14), lymph nodal metastasis (n = 4), and abdominal wall metastasis (n = 2). In detecting recurrent ovarian tumor, patient-based sensitivity and the accuracy of PET/CT and MRI were 73% and 91% (P < 0.05), and 81% and 89% (P > 0.05), respectively. In addition, overall lesion-based sensitivity of PET/CT and MRI were 66% and 86%, respectively (P < 0.05). In detecting peritoneal lesions, overall lesion-based sensitivity and accuracy of PET/CT and MRI for peritoneal lesions were 43% and 86%, and 75% and 94%, respectively (P < 0.05). CONCLUSIONS: Magnetic resonance imaging is more sensitive than PET/CT for detecting local pelvic recurrence and peritoneal lesions of recurrent ovarian tumors. |
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Authors:
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Chan Kyo Kim; Byung Kwan Park; Joon Young Choi; Byoung-Gie Kim; Heon Han |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 31 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2007 Nov-Dec |
Date Detail:
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Created Date: 2007-11-28 Completed Date: 2008-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 868-75 Citation Subset: IM |
Affiliation:
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Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Neoplasms
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secondary Adult Aged Antineoplastic Combined Chemotherapy Protocols / therapeutic use Cystadenocarcinoma, Papillary / diagnosis, radionuclide imaging Female Fluorodeoxyglucose F18 / diagnostic use Follow-Up Studies Humans Image Processing, Computer-Assisted / methods Lymphatic Metastasis / diagnosis, radionuclide imaging Magnetic Resonance Imaging* Middle Aged Neoadjuvant Therapy Neoplasm Invasiveness Neoplasm Recurrence, Local / diagnosis*, radionuclide imaging Ovarian Neoplasms / diagnosis*, radionuclide imaging Peritoneal Neoplasms / diagnosis, radionuclide imaging Positron-Emission Tomography* / methods Radiopharmaceuticals / diagnostic use Retrospective Studies Sensitivity and Specificity Tomography, X-Ray Computed* / methods |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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