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Detection of pulmonary nodules by C-arm CT using a phantom lung: comparison with CT.
MedLine Citation:
PMID:  21969706     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BackgroundEvaluation of detection of lung nodules by C-arm CT (CACT) is important before this procedure can be used to guide percutaneous lung interventions.PurposeTo compare the efficacy of CACT with CT in the detection of pulmonary nodules using a phantom lung.Material and MethodsA phantom lung containing 12 phantom nodules in four sizes (5 mm/8 mm/10 mm/12 mm) and three CT values (one solid nodule, +100 HU; two ground glass nodules, -630 and -800 HU) was used. Six sessions of CACT (slice thickness 4.5 mm) and CT (slice thickness 5 mm) were performed. In each session, the locations of nodules were arbitrarily changed in the phantom. Three radiologists assessed the detection of a total of 72 nodules. Statistical analysis was performed for the sensitivity and positive predictive value of lung nodules between CACT and CT by the McNemar test and paired t-test (P < 0.05).ResultsSensitivity did not differ between CACT and CT, respectively (reader 1, 82% vs. 88%, P = 0.22; reader 2, 82% vs. 78%, P = 0.37; reader 3, 79% vs. 83%, P = 0.48). For nodules of 8 mm or larger, the sensitivity increased for each reader and showed no significant difference between CACT vs. CT. The positive predictive value did not differ between CACT and CT.ConclusionIn this phantom study, CT and CACT show similar sensitivity for the detection of pulmonary nodules. CACT could be used in percutaneous interventional procedures in the lungs.
Authors:
Hiroki Higashihara; Keigo Osuga; Takeo Azuma; Tetsuro Nakazawa; Masahiro Yanagawa; Ayano Kikuyama; Noboru Maeda; Noriyuki Tomiyama
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-3
Journal Detail:
Title:  Acta radiologica (Stockholm, Sweden : 1987)     Volume:  -     ISSN:  1600-0455     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706123     Medline TA:  Acta Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, Osaka.
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