Document Detail


Detection of non-genotoxic carcinogens using ras-transfected bhas 42 cells.
MedLine Citation:
PMID:  17492230     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The cell transformation test employing Bhas 42 cells (v-Ha-ras-transfected BALB/c 3T3 cells) was shown to be a sensitive screening method for the detection of chemicals with different mechanisms of transforming potential. Because of the simplicity of the procedure, it is anticipated that further investigations on Bhas assays will open ways of not only detecting non-genotoxic carcinogens but also of elucidating mechanisms of carcinogenesis.
Authors:
Makoto Umeda
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ALTEX : Alternativen zu Tierexperimenten     Volume:  23 Suppl     ISSN:  0946-7785     ISO Abbreviation:  ALTEX     Publication Date:  2006  
Date Detail:
Created Date:  2007-05-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100953980     Medline TA:  ALTEX     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  450-5     Citation Subset:  IM    
Affiliation:
Hatano Research Institute, Food and Drug Safety Center, Kanagawa, Japan.
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