| Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. | |
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MedLine Citation:
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PMID: 20122515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Of 31 patients with lung cancer, 19 underwent PET-CT and 12 had CT followed by PET. Thoracic lymph nodes were sampled by mediastinoscopy or thoracotomy. Sensitivities, specificities, positive (PPV), and negative predictive values (NPV) were calculated based on histopathology. Ninety nodes (41 malignant) were identified. Sensitivity, specificity, PPV, and NPV were 94%, 73%, 66%, and 96% for PET-CT, respectively. In 12 patients who underwent PET and CT separately, these values were 90%, 31%, 64%, and 71% for PET and 81%, 50%, 69%, and 66% for CT, respectively. |
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Authors:
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Elisa Ventura; Tina Islam; Michael S Gee; Umar Mahmood; Marta Braschi; Mukesh G Harisinghani |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Clinical imaging Volume: 34 ISSN: 1873-4499 ISO Abbreviation: Clin Imaging Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-04-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911831 Medline TA: Clin Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 20-8 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Carcinoma, Non-Small-Cell Lung / diagnosis*, secondary* Female Humans Lung Neoplasms / diagnosis* Lymph Nodes / radiography, radionuclide imaging Lymphatic Metastasis Male Middle Aged Positron-Emission Tomography / methods* Reproducibility of Results Sensitivity and Specificity Subtraction Technique* Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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