Document Detail


Detection of myocardial viability using stress echocardiography.
MedLine Citation:
PMID:  9183619     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Asynergic myocardial regions in patients with coronary artery disease can be viable. They may have the ability to improve their function after restoring coronary blood flow. Asynergic but viable myocardial regions have a positive inotropic reserve which can be stimulated by catecholamines. Because echocardiography is an established method for evaluating regional left ventricular function, it has the potential to detect the inotropic response of asynergic myocardial regions. In the clinical setting, prediction of left ventricular functional improvement after revascularization is particularly important. Dobutamine stress echocardiography is the most frequently used stress echocardiographic test for detection of myocardial viability. Dobutamine is infused at low rates of 2.5 to 20 micrograms.kg-1.min-1 to detect myocardial viability. This paper reports on the sensitivity and specificity of the method for the detection of viability and its usefulness for prediction of left ventricular functional improvement after revascularization.
Authors:
W Krahwinkel; T Ketteler; J Wolfertz; J Gödke; I Krakau; L J Ulbricht; W Mecklenbeck; H Gülker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European heart journal     Volume:  18 Suppl D     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-08-21     Completed Date:  1997-08-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  D111-6     Citation Subset:  IM    
Affiliation:
Wuppertal Heart Centre, Department of Cardiology, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cardiotonic Agents / diagnostic use*
Dobutamine / diagnostic use*
Echocardiography / methods*
Exercise Test / methods*
Female
Humans
Male
Middle Aged
Myocardial Infarction / diagnosis*
Myocardial Stunning / diagnosis*
Myocardium / pathology
Predictive Value of Tests
Sensitivity and Specificity
Ventricular Function, Left / physiology
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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