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Detection of mobile genetic elements in pediocin PA-1 like producing lactic acid bacteria.
MedLine Citation:
PMID:  22915312     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
To evaluate the presence of mobile genetic elements in intergeneric and interspecific pediocin producing lactic acid bacteria (LAB) the flanking regions of the pediocin PA-1/AcH (pediocin PA-1) operon was characterized. In Enterococcus faecium Acr4 and Lactobacillus plantarum Acr2 a variation in the amplicon size in the downstream region of the operon was identified, suggesting a deletion in this region. Beyond that, in pediocin PA-1 encoding plasmids mobile genetic elements such as ISLpl 1 and mobilization regions were detected by Southern hybridization analysis. Phylogenetic analyses of the E. faecium Acr4 ISLpl 1 gene sequence suggested the gene transfer from lactobacilli in the environment. The tyrosine recombinase detected in pediocin plasmids of P. acidilactici H and K7 indicate a possible transfer of the entire operon among LAB. Since these elements are known to be associated with transfer of genes linked to the bacteriocin production, antibiotic resistance and sugar utilization, we suggest similar mechanism for natural spread of pediocin PA-1 operon among different bacterial species. (© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim).
Authors:
Sundru Manjulata Devi; Prakash M Halami
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-23
Journal Detail:
Title:  Journal of basic microbiology     Volume:  -     ISSN:  1521-4028     ISO Abbreviation:  J. Basic Microbiol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503885     Medline TA:  J Basic Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Food Microbiology Department, CSIR-Central Food Technological Research Institute, Mysore 570020, India.
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