Document Detail


Detection of liver metastases secondary to pancreatic cancer: utility of combined helical computed tomography during arterial portography with biphasic computed tomography-assisted hepatic arteriography.
MedLine Citation:
PMID:  20635101     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: This study was designed to define the diagnostic advantage of computed tomography during arterial portography (CTAP) combined with computed tomography-assisted hepatic arteriography (CTHA) for the preoperative detection of liver metastases secondary to pancreatic cancer compared with that of multidetector computed tomography (MDCT).
METHODS: From January 2002 to December 2007, we retrospectively studied 197 consecutive patients with pancreatic cancer. MDCT was performed on 192 patients prior to preoperative visceral angiography; 153 patients underwent CTAP + CTHA at the time of preoperative angiography.
RESULTS: Liver metastases were identified in 39 patients by means of MDCT. Of the 153 patients who had no evidence of liver metastases on MDCT, 129 patients underwent CTAP + CTHA, and 53 of these 129 patients (41.1%) were diagnosed as having liver metastases that could not be detected by MDCT. These tumors missed by MDCT ranged from 3 to 15 mm in size. On CTAP + CTHA, a solitary nodule in the liver was detected in 11 patients, 2 nodules were detected in 6 patients, 3 lesions were detected in 2 patients, and ≧4 lesions were detected in 34 patients. The sensitivity and specificity of CTAP + CTHA versus MDCT were 94.2 versus 48.4% and 82.7 versus 97.9%, respectively.
CONCLUSIONS: The combination of CTAP and CTHA is useful to confirm liver metastases and can potentially offer more accurate staging of pancreatic cancer compared with MDCT.
Authors:
Yoshiaki Ikuta; Hiroshi Takamori; Osamu Ikeda; Hiroshi Tanaka; Yasuo Sakamoto; Daisuke Hashimoto; Nobuyuki Ozaki; Osamu Nakahara; Satoshi Furuhashi; Shinya Abe; Toru Beppu; Shinya Shimada; Yasuyuki Yamashita; Hideo Baba
Publication Detail:
Type:  Journal Article     Date:  2010-07-16
Journal Detail:
Title:  Journal of gastroenterology     Volume:  45     ISSN:  1435-5922     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1241-6     Citation Subset:  IM    
Affiliation:
Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.
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