| Detection of hypervascular malignant foci in borderline lesions of hepatocellular carcinoma: comparison of dynamic multi-detector row CT, dynamic MR imaging and superparamagnetic iron oxide-enhanced MR imaging. | |
| | |
MedLine Citation:
|
PMID: 18386012 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The study object was to retrospectively compare the detection rate of hypervascular foci visualized by CT during hepatic arteriography (CTHA) in borderline nodules, which was observed upon cirrhotic livers, on dynamic MDCT, dynamic gadolinium-enhanced MR (dynamic MR), and SPIO-enhanced MR imaging. Eighty-five nodules in 49 patients with cirrhosis were evaluated. When a part of the nodule showed hyperdensity relative to the surrounding areas of the nodule on CTHA, it was defined as "hypervascular focus." The relationships between the dynamic MDCT and dynamic MR and SPIO-enhanced MR imaging findings of these foci were analyzed using X(2) test. Hypervascular foci were detected in 17 (53%) of 32 on the arterial dominant phase of dynamic MDCT, in 19 (37%) of 51 on the arterial dominant phase of dynamic MR and in 6 (26%) of 23 on SPIO-enhanced MR imaging. Arterial dominant phase of dynamic MDCT demonstrated a significantly higher detection rate of hypervascular foci less than 5 mm in diameter than did dynamic and SPIO MR imaging (p<0.05). Hypervascular foci in borderline nodules could be better visualized by dynamic MDCT than by gadolinium- and SPIO-enhanced MR imaging. Dynamic MDCT is recommended for the follow-up examination of hypovascular borderline lesions. |
| | |
Authors:
|
Rieko Shinmura; Osamu Matsui; Masumi Kadoya; Satoshi Kobayashi; Noboru Terayama; Junichiro Sanada; Hiroshi Demachi; Toshifumi Gabata |
Publication Detail:
|
Type: Comparative Study; Evaluation Studies; Journal Article Date: 2008-04-02 |
Journal Detail:
|
Title: European radiology Volume: 18 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2008 Sep |
Date Detail:
|
Created Date: 2008-08-05 Completed Date: 2009-01-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
|
Languages: eng Pagination: 1918-24 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Toyama Prefectural Central Hospital, 2-2-78 Nishinagae, Toyama, 930-8550, Japan. rieko@rad.m.kanazawa-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Carcinoma, Hepatocellular / blood supply, diagnosis* Contrast Media Female Ferric Compounds / diagnostic use* Humans Liver Neoplasms / blood supply, diagnosis* Magnetic Resonance Imaging / methods* Male Middle Aged Neovascularization, Pathologic / diagnosis* Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Ferric Compounds; 1309-37-1/ferric oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: From single cells to tissue architecture-a bottom-up approach to modelling the spatio-temporal organ...
Next Document: Radiological profile of anemia on unenhanced MDCT of the thorax.