Document Detail


Detection of human herpesvirus 6 DNA in throat swabs by polymerase chain reaction.
MedLine Citation:
PMID:  2177778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The detection of human herpesvirus 6 (HHV-6) DNA was carried out in throat swabs of adults and children by the polymerase chain reaction, and isolation of virus was also attempted from peripheral mononuclear cells. Although virus was isolated only from peripheral blood mononuclear cells of infants with exanthem subitum, HHV-6 DNA was detected in one of 30 healthy adults (3%), two of nine adults (22%) with common cold, two of 10 infants (20%) with exanthem subitum, four of 39 febrile children (10%) with antibody to HHV-6 (including three of 10 infants aged under 1 year old, and one of 29 children aged over 1 year old). However, HHV-6 DNA was not detected in samples from healthy neonates.
Authors:
S Kido; K Kondo; T Kondo; T Morishima; M Takahashi; K Yamanishi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical virology     Volume:  32     ISSN:  0146-6615     ISO Abbreviation:  J. Med. Virol.     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-03-08     Completed Date:  1991-03-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7705876     Medline TA:  J Med Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  139-42     Citation Subset:  IM    
Affiliation:
Department of Virology, Osaka University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Base Sequence
Common Cold / microbiology
DNA, Viral / analysis*,  chemistry
Exanthema Subitum / microbiology
Herpesvirus 6, Human / genetics,  isolation & purification*
Humans
Infant
Infant, Newborn
Leukocytes, Mononuclear / microbiology
Middle Aged
Molecular Sequence Data
Pharynx / microbiology*
Polymerase Chain Reaction
Chemical
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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