Document Detail

Detection of hepatitis E virus (HEV) in a demographic managed wild boar (Sus scrofa scrofa) population in Italy.
MedLine Citation:
PMID:  17706898     Owner:  NLM     Status:  MEDLINE    
Hepatitis E virus (HEV) is the causative agent of Hepatitis E. Swine and human HEV strains are genetically related, suggesting the occurrence of zoonotic transmission. Recently, in Japan, cases of food-borne HEV transmission have been described in people after consuming raw or undercooked meat from wild boars or pigs. Although, swine HEV strains have been detected in pig herds in many European countries, only minimal information is presently available about the circulation and the prevalence of HEV in wild boars in Europe. In this study, we investigated the presence of HEV in a demographic managed wild boar population in Italy. Detection of HEV RNA was accomplished using a nested reverse-transcription polymerase chain reaction on bile samples from 88 shot animals. HEV RNA was detected in 22 out of 88 animals tested (25%). Phylogenetic analysis on the nucleotide sequences obtained from 10 positive PCR products indicated that only one HEV strain was circulating in the wild boar population considered, and that this strain was closer to human and swine HEV strains circulating in Europe than to wild boar Japanese strains.
Francesca Martelli; Andrea Caprioli; Martina Zengarini; Andrea Marata; Caterina Fiegna; Ilaria Di Bartolo; Franco Maria Ruggeri; Mauro Delogu; Fabio Ostanello
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-07-10
Journal Detail:
Title:  Veterinary microbiology     Volume:  126     ISSN:  0378-1135     ISO Abbreviation:  Vet. Microbiol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-23     Completed Date:  2008-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705469     Medline TA:  Vet Microbiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  74-81     Citation Subset:  IM    
Department of Veterinary Public Health and Animal Pathology, Faculty of Veterinary Medicine, Bologna University, Via Tolara di Sopra 50, 40064 Ozzano Emilia (BO), Italy.
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MeSH Terms
Bile / virology
Genome, Viral
Hepatitis E / epidemiology,  veterinary*,  virology
Hepatitis E virus / genetics,  isolation & purification*
Italy / epidemiology
Sus scrofa
Swine Diseases / epidemiology,  virology*

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