| Detection of hemophilia A carriers by use of frozen plasma samples. | |
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MedLine Citation:
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PMID: 688629 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The efficacy of using promptly frozen plasma samples in the diagnosis of the carrier state for hemophilia A was evaluated by simultaneous measurement of factor VIII acitivity and antigen in 20 normal women and 20 obligate carriers. Factor VIII antigen was measured by two methods, electroimmunoassay and immunoradiometric assay. When the factor VIII activity and antigen data were evaluated by regression analysis, 94% of the carriers were correctly identified at the 95% confidence level. |
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Authors:
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H C Yang; J Hardin; C Vaudreuil |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical chemistry Volume: 24 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 1978 Sep |
Date Detail:
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Created Date: 1978-12-02 Completed Date: 1978-12-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1628-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigens
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analysis Factor VIII / analysis* Female Freezing Hemophilia A / blood, diagnosis*, genetics Heterozygote Detection* / methods Humans Plasma |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 9001-27-8/Factor VIII |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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