| DETECTION OF GLUCOSE ABNORMALITIES IN PATIENTS WITH ACUTE CORONARY HEART DISEASE: STUDY OF RELIABLE TOOLS IN CLINICAL PRACTICE. | |
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MedLine Citation:
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PMID: 21646857 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aim: To investigate the prevalence of glucose abnormalities in patients with acute coronary syndrome and to assess the reliability of certain clinical or analytical variables to predict a pathologic result of oral glucose tolerance test (OGTT) three months from discharge. Subjects and Methods: Prospective study of 102 patients admitted to the coronary care units. Patients were classified according to the American Diabetes Association criteria. Three months after discharge an OGTT was performed to non-DM patients. Results: 46 (45.1%) patients were identified as diabetic (5 previously undiagnosed) and 56 (54.9%) as non-diabetic. OGTT identified 22% of diabetes, 33% of impaired glucose tolerance and 45% of normal glucose tolerance. Fasting glucose (r= 0.55, p<0.001), HbA1c (r= 0.46, p<0.001), Low HDL-c levels (r= -0.34, p<0.02), waist-hip ratio (r= 0.45, p<0.01), high systolic blood pressure (r= 0.5, p<0.01), and presence of acute MI (r= 0.46, p<0.001) at admission resulted significant to predict a pathologic result of OGTT. Conclusions: Glucose abnormalities are frequent in acute coronary syndrome patients. Certain clinical and analytical markers at admission such as fasting glucose, HbA1c, HDL-c < 40 mg/dL, waist-hip ratio and systolic blood pressure, recognize patients with a higher predisposition to present a pathologic result in OGTT three months from discharge. |
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Authors:
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M I Del Olmo; J F Merino-Torres; M Argente; A Ramos; M S Navas; V Campos; V R Cámara; A Pérez-Lázaro |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-30 |
Journal Detail:
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Title: Journal of endocrinological investigation Volume: - ISSN: 1720-8386 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-6-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7806594 Medline TA: J Endocrinol Invest Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Endocrinology and Nutrition. University Hospital La Fe. Valencia. Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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