Document Detail


Detection of embolic particles with the Doppler guide wire during coronary intervention in patients with acute myocardial infarction: efficacy of distal protection device.
MedLine Citation:
PMID:  15653017     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: We investigated whether embolic particles could be detected as high-intensity transient signals (HITS) with a Doppler guide wire during percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) We also assessed whether these signals could be reduced using a distal protection (DP) device. BACKGROUND: Embolization of thrombi and plaque components to the microcirculation is a major complication of PCI in patients with AMI. Embolic particles running in the cerebral artery are detected as HITS by transcranial Doppler ultrasound. METHODS: We prospectively studied 16 consecutive patients with AMI who underwent direct PCI within 24 h after the onset of symptoms. A PercuSurge GuardWire (MedtronicAVE, Santa Rosa, California) was used as the DP device. Eight patients were randomly assigned to the non-DP group, and the remaining eight were assigned to the DP group. Coronary flow velocity was recorded continuously from before the first balloon inflation to after balloon deflation. RESULTS: All patients in the non-DP group had HITS detected (12 +/- 9 counts) within five consecutive beats (4 +/- 1 beat) after balloon deflation, but none were detected in any of the patients in the DP group. CONCLUSIONS: The Doppler guide wire can be used to visually detect and count emboli as HITS, and the DP device is effective for prevention of distal embolization.
Authors:
Atsunori Okamura; Hiroshi Ito; Katsuomi Iwakura; Shigeo Kawano; Koichi Inoue; Yoshihiro Maekawa; Toshio Ogihara; Kenshi Fujii
Related Documents :
24886207 - A novel treatment strategy of new onset atrial fibrillation after cardiac surgery: an o...
25114327 - Serial hemodynamic measurements in post-cardiac arrest cardiogenic shock treated with t...
21095287 - Thrombus aspiration followed by direct stenting: a novel strategy of primary percutaneo...
24701417 - Pyruvate-fortified resuscitation stabilizes cardiac electrical activity and energy meta...
11015337 - 17beta-estradiol decreases endothelin-1 levels in the coronary circulation of postmenop...
954817 - The positive inotropic and chronotropic actions of some amino acids and their effects i...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  45     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-17     Completed Date:  2005-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  212-5     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, Sakurabashi Watanabe Hospital, 2-4-32 Umeda, Kita-ku, Osaka 530-0001, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects*,  instrumentation*
Blood Flow Velocity
Coronary Circulation
Embolism / etiology,  prevention & control*,  ultrasonography*
Female
Heart Catheterization
Humans
Male
Middle Aged
Myocardial Infarction / therapy*
Prospective Studies
Ultrasonography, Doppler, Duplex
Ultrasonography, Interventional*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Intravascular ultrasound-guided treatment for angiographically indeterminate left main coronary arte...
Next Document:  Pressure-derived measurement of coronary flow reserve.