Document Detail

Detection of elastin-antielastin circulating immune complexes (CIC) in diabetic patients with vascular damage.
MedLine Citation:
PMID:  3229119     Owner:  NLM     Status:  MEDLINE    
Healthy subjects aged between 25 and 60 (20 cases) and between 61 and 65 (5 cases), and diabetic patients with vascular damage, aged between 24 and 62 (6 cases), were tested by a new method for the detection and identification of elastin-antielastin circulating immune complexes (CIC) in human sera. Such immune complexes were found in all patients' sera and only in one of the controls (at the age of 65). Among different patients, the elastin-antielastin CIC varied in size and elastin content, showing some correlation between these two characteristics and the existence of microvascular complications, as proved by the clinical and paraclinical investigation of the patients.
S Baydanoff; G Nicoloff; T Russev; C Alexiev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  30     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1988  
Date Detail:
Created Date:  1989-04-14     Completed Date:  1989-04-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
Department of Biology, University School of Medicine, Pleven, Bulgaria.
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MeSH Terms
Antigen-Antibody Complex / analysis*
Diabetes Complications
Diabetic Angiopathies / immunology*
Elastin / analysis,  immunology*
Middle Aged
Vascular Diseases / complications
Reg. No./Substance:
0/Antigen-Antibody Complex; 9007-58-3/Elastin

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