Document Detail

Detection of coronary artery disease using 12-lead electrocardiogram and simultaneous dual myocardial imaging with iodine-123-beta-methyl iodophenyl-pentadecanoic acid (BMIPP) and thallium-201 in patients with unstable angina.
MedLine Citation:
PMID:  8774965     Owner:  NLM     Status:  MEDLINE    
We investigated the usefulness of 12-lead electrocardiogram and simultaneous single-photon emission computed tomography (SPECT) with 123I-beta-methyl iodophenyl-pentadecanoic acid (BMIPP) and thallium-201 (201Tl) for detecting coronary artery disease (CAD) in 54 consecutive patients with unstable angina. Discordant BMIPP uptake was defined as less 123I-BMIPP uptake than 201Tl uptake in 123I-BMIPP/201Tl dual SPECT. In the detection of CAD, ischemic electrocardiographic change during anginal attack had high sensitivity and low specificity, while discordant BMIPP finding had low sensitivity and high specificity. In patients showing ST depression during anginal attack, discordant BMIPP uptake showed high sensitivity and high specificity for detecting CAD. In conclusion, both 12-lead electrocardiogram during anginal attack and discordant BMIPP uptake are useful in detecting CAD in patients with unstable angina.
M Saitoh; K Hasegawa; K Hasegawa; T Kondoh; T Yanagawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  34     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-12-04     Completed Date:  1996-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1064-70     Citation Subset:  IM    
Department of Internal Medicine, Nishio Municipal Hospital.
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MeSH Terms
Aged, 80 and over
Angina, Unstable / physiopathology*,  radiography,  radionuclide imaging*
Coronary Angiography
Fatty Acids / diagnostic use*
Iodine Radioisotopes / diagnostic use*
Iodobenzenes / diagnostic use*
Middle Aged
Retrospective Studies
Sensitivity and Specificity
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Fatty Acids; 0/Iodine Radioisotopes; 0/Iodobenzenes; 116754-87-1/iodofiltic acid

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