Document Detail

Detection of cancer cervix by estimation of sialic acid.
MedLine Citation:
PMID:  16570760     Owner:  NLM     Status:  MEDLINE    
The study was undertaken to determine the sialic acid concentration of cervical tissue and serum of women with healthy and unhealthy cervix. The sialic acid value in local tissue of cervix and in serum showed slight elevation in benign inflammatory lesions, moderate elevation was found in severe dysplasia and preinvasive carcinoma and marked elevation in invasive carcinoma cervix. The values, both in the serum and in the cervical tissue, increased gradually with the advancement of grading of frank malignancy. The elevation of sialic acid in the serum was slow to start with but persisted for a longer period, wereas the concentration in local tissue was found to be increasing with the pathological process.
Anita Roy; Somajita Chakraborty
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Indian Medical Association     Volume:  103     ISSN:  0019-5847     ISO Abbreviation:  J Indian Med Assoc     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-03-30     Completed Date:  2006-05-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505608     Medline TA:  J Indian Med Assoc     Country:  India    
Other Details:
Languages:  eng     Pagination:  589-90     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Medical College and Hospital, Kolkata.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carcinoma / blood,  diagnosis
Case-Control Studies
Cervix Uteri / pathology*
N-Acetylneuraminic Acid / blood*
Obstetrics and Gynecology Department, Hospital
Time Factors
Uterine Cervical Dysplasia / blood,  diagnosis
Uterine Cervical Neoplasms / blood,  diagnosis*
Reg. No./Substance:
131-48-6/N-Acetylneuraminic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Risk factor analysis in ischaemic stroke: a hospital-based study.
Next Document:  Epidemiological aspects of prediabetes--review of the current data.