| Detection of anthralin in skin during treatment. | |
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MedLine Citation:
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PMID: 3869415 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Free anthralin was detected in the stratum corneum and in hair follicles in histological sections of patients with psoriasis undergoing short contact therapy. A solution of sodium borate was used to provoke a yellow fluorescent complex. There was a strong fluorescence especially on the plaques and anthralin could be detected in psoriatic plaques up to 48 hours after treatment. It was difficult to completely eliminate the drug by washing with soap and anthralin could even be detected on non-treated areas. |
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Authors:
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L Juhlin; B Schroot |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica. Supplementum Volume: 120 ISSN: 0365-8341 ISO Abbreviation: Acta Derm Venereol Suppl (Stockh) Publication Date: 1985 |
Date Detail:
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Created Date: 1986-06-10 Completed Date: 1986-06-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370311 Medline TA: Acta Derm Venereol Suppl (Stockh) Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 27-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Aged Anthracenes / therapeutic use* Anthralin / administration & dosage, analysis, therapeutic use* Borates Humans Microscopy, Fluorescence Middle Aged Psoriasis / drug therapy* Skin / analysis* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anthracenes; 0/Borates; 1330-43-4/sodium borate; 480-22-8/Anthralin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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