Document Detail


Detection and amplification of chirality by helical polymers.
MedLine Citation:
PMID:  14695548     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A unique feature of synthetic helical polymers for the detection and amplification of chirality is briefly described in this article. In sharp contrast to host-guest and supramolecular systems that use small synthetic receptor molecules, chirality can be significantly amplified in a helical polymer, such as poly(phenylacetylene)s with functional pendants, which enable the detection of a tiny imbalance in biologically important chiral molecules through a noncovalent bonding interaction with high cooperativity. The rational design of polymeric receptors can be possible by using chromophoric helical polymers combined with functional groups as the pendants, which target particular chiral guest molecules for developing a highly efficient chirality-sensing system. The chirality sensing of other small molecular and supramolecular systems is also briefly described for comparison.
Authors:
Eiji Yashima; Katsuhiro Maeda; Tatsuya Nishimura
Related Documents :
18655088 - Dinuclear zinc-catalyzed asymmetric desymmetrization of acyclic 2-substituted-1,3-propa...
7275898 - Application of chiral lanthanide nuclear magnetic resonance shift reagents to pharmaceu...
11531578 - Mesoscopic correlation of supramolecular chirality in one-dimensional hydrogen-bonded a...
11126298 - Parallel solid-phase synthesis and structural characterization of a library of highly s...
11983968 - Catena-poly[[bis(cis-1-tert-butyltetrazole-kappan4)copper(ii)]-di-micro-chloro].
22376298 - How amidoximate binds the uranyl cation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  10     ISSN:  0947-6539     ISO Abbreviation:  Chemistry     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2003-12-25     Completed Date:  2004-09-30     Revised Date:  2009-08-04    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  42-51     Citation Subset:  -    
Affiliation:
Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya 464-8603, Japan. yashima@apchem.nagoya-u.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Promises and problems of mesoscale materials chemistry or why meso?
Next Document:  Synthesis of novel chiral and acentric coordination polymers by the reaction of zinc or cadmium salt...