Document Detail

Detection of Pneumocystis carinii f. sp. hominis and viruses in presumably immunocompetent infants who died in the hospital or in the community.
MedLine Citation:
PMID:  15593013     Owner:  NLM     Status:  MEDLINE    
Fresh-frozen lung and tracheal-aspirate specimens obtained from 112 infants who died in Santiago, Chile, during 1998-2000 were analyzed for the presence of Pneumocystis DNA, by use of nested DNA amplification of the large subunit mitochondrial rRNA, and for the presence of viruses, by use of culture and immunofluorescence. Pneumocystis DNA was detected in specimens from 45 (51.7%) of 87 infants who died in the community and from 5 (20%) of 25 infants who died in the hospital (P=.006). Primary infection with Pneumocystis was highly frequent among infants who die unexpectedly in the community. Infection with viruses was more common in infants who died in the hospital.
Sergio L Vargas; Carolina A Ponce; Vivian Luchsinger; Cecilia Silva; Myriam Gallo; René López; José Belletti; Luis Velozo; Ricardo Avila; Maria A Palomino; Samuel Benveniste; Luis F Avendaño
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-12-06
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  191     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-13     Completed Date:  2005-01-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  AIM; IM    
Programas de Microbiologia, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
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MeSH Terms
DNA, Fungal / analysis
DNA, Mitochondrial / analysis
DNA, Ribosomal / analysis
Fluorescent Antibody Technique
Infant, Newborn
Lung / microbiology,  virology
Pneumocystis jirovecii / genetics,  isolation & purification*
Pneumonia, Pneumocystis / epidemiology*
Sudden Infant Death / etiology*
Trachea / microbiology,  virology
Virus Diseases / epidemiology*
Viruses / genetics,  growth & development,  isolation & purification*
Reg. No./Substance:
0/DNA, Fungal; 0/DNA, Mitochondrial; 0/DNA, Ribosomal

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