| Detection of Hepatic Metastases Using Dual-Time-Point FDG PET/CT Scans in Patients with Colorectal Cancer. | |
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MedLine Citation:
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PMID: 20683670 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to determine the most useful parameter of dual-time-point 2-deoxy-2-[(18)F]fluoro-D: -glucose positron emission tomography/computed tomography (PET/CT) for detection of hepatic metastases in patients with colorectal cancer. PROCEDURES: Thirty-nine patients had undergone a dual-time-point PET/CT scan and a subsequent histopathological confirmation for a workup of hepatic metastases. Detection rates were compared for visual analysis score, standardized uptake value (SUV), tumor-to-liver uptake ratio (TLR), and percent changes of the SUV and TLR. RESULTS: Of 91 liver lesions, 86 lesions were confirmed as metastases. The SUV and TLR of metastatic lesions on the delayed images were higher than those on the first scan (p < 0.001). The signal-to-noise ratio of the delayed PET scan was higher than that of the first scan (p < 0.0001). The TLR and SUV of the delayed scan showed the highest detection rates of 92% and 88%, whereas percent changes of SUV and TLR showed the lowest detection rates (51%, 67%). Visual analysis detected 87% on the delayed scan and 77% on the first scan. CONCLUSIONS: A delayed scan is more favorable for the detection of hepatic metastases of colorectal cancer, and the TLR on the delayed scan was the most useful parameter. |
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Authors:
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Jeong Won Lee; Seok-Ki Kim; Sang Mi Lee; Seung Hwan Moon; Tae-Sung Kim |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Volume: 13 ISSN: 1860-2002 ISO Abbreviation: Mol Imaging Biol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101125610 Medline TA: Mol Imaging Biol Country: United States |
Other Details:
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Languages: eng Pagination: 565-72 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Jeju National University Hospital, Jeju, Jeju Special Self-Governing Province, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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