| Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatous plaques. | |
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MedLine Citation:
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PMID: 1519134 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is serological evidence that a recently described new strain of Chlamydia, namely Chlamydia pneumoniae TWAR, is associated with coronary artery disease. This study describes the detection of TWAR organisms in the coronary arterial fatty streaks and atheromatous plaques in 7 autopsy cases. TWAR-like organisms were observed ultrastructurally in the lipid-rich core area of fibrolipid plaques and in intimal smooth-muscle cells. In 5 cases, immunoperoxidase staining showed positive reactions to Chlamydia genus- and C. pneumoniae species-specific monoclonal antibodies. |
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Authors:
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A Shor; C C Kuo; D L Patton |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 82 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 1992 Sep |
Date Detail:
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Created Date: 1992-10-06 Completed Date: 1992-10-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: SOUTH AFRICA |
Other Details:
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Languages: eng Pagination: 158-61 Citation Subset: IM |
Affiliation:
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National Centre for Occupational Health, Johannesburg. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chlamydophila pneumoniae / isolation & purification* Coronary Artery Disease / microbiology* Coronary Vessels / microbiology* Histocytochemistry Humans Immunohistochemistry Male |
| Grant Support | |
ID/Acronym/Agency:
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AI-21885/AI/NIAID NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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