Document Detail


Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatous plaques.
MedLine Citation:
PMID:  1519134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is serological evidence that a recently described new strain of Chlamydia, namely Chlamydia pneumoniae TWAR, is associated with coronary artery disease. This study describes the detection of TWAR organisms in the coronary arterial fatty streaks and atheromatous plaques in 7 autopsy cases. TWAR-like organisms were observed ultrastructurally in the lipid-rich core area of fibrolipid plaques and in intimal smooth-muscle cells. In 5 cases, immunoperoxidase staining showed positive reactions to Chlamydia genus- and C. pneumoniae species-specific monoclonal antibodies.
Authors:
A Shor; C C Kuo; D L Patton
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  82     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-10-06     Completed Date:  1992-10-06     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  158-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chlamydophila pneumoniae / isolation & purification*
Coronary Artery Disease / microbiology*
Coronary Vessels / microbiology*
Histocytochemistry
Humans
Immunohistochemistry
Male
Grant Support
ID/Acronym/Agency:
AI-21885/AI/NIAID NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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