Document Detail

Detection of carotid artery plaque ulceration using 3-dimensional ultrasound.
MedLine Citation:
PMID:  19888925     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Three-dimensional (3D) ultrasound imaging is a new technique that maximizes the information and image quality of traditional 2-dimensional (2D) B-mode scanning. The aim of this study was to evaluate the ability of the 3D ultrasound technique to characterize ulcerated atherosclerotic carotid plaque.
METHODS: Using conventional 2D ultrasound, we examined 284 carotid arteries from 142 consecutive patients (101 men and 41 women; average age, 64 years). Eighty-two carotid arteries were symptomatic with atherosclerotic plaque causing 50-99% stenosis. In 62 arteries, the atherosclerotic plaques were visualized completely and were further processed to construct 3D images. Two independent observers rated plaque morphology according to a standardized protocol.
RESULTS: The 3D ultrasound showed carotid plaque ulceration more frequently than the 2D method (16.1% and 14.5% of plaques, for observers 1 and 2, respectively, versus 6.5% and 9.7% of plaques, for observers 1 and 2, respectively, P= .125 and P= .063, for observers 1 and 2, respectively). The interobserver reproducibility was very good for both methods (κ= .973, SE = .027, P < .001 for 3D, and κ= .885, SE = .055, P < .001 for 2D), although the 3D method was slightly superior to 2D.
CONCLUSIONS: 3D ultrasound reliably characterized the surface morphology of atherosclerotic carotid plaques. A trend of superiority of 3D ultrasound over 2D was found in detecting ulcers of carotid artery plaque.
John Heliopoulos; Konstantinos Vadikolias; Charitomeni Piperidou; Panayiotis Mitsias
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  21     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  126-31     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 by The American Society of Neuroimaging.
From the Department of Neurology, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece (JH, KV, CP); Stroke and Neurovascular Center, Department of Neurology, Henry Ford Health System, Detroit, Michigan (PM).
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