| Detection of aortic regurgitation with 64-slice multidetector computed tomography (MDCT). | |
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MedLine Citation:
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PMID: 20605488 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RATIONALE AND OBJECTIVES: To determine the diagnostic accuracy of 64-row multidetector cardiac computed tomography (MDCT) in detecting aortic regurgitation (AR) on prospectively acquired images with trans-thoracic echocardiography (TTE) as a reference standard. MATERIALS AND METHODS: Forty-three consecutive patients underwent MDCT and TTE. AR was defined on MDCT images acquired at 75% phase of R-R interval as the lack of aortic cusps coaptation. The maximum regurgitant orifice area (ROA) was planimetered and compared to TTE. RESULTS: All 29 patients with AR on TTE were correctly identified by MDCT. The sensitivity, specificity, positive predictive value, and negative predictive value of MDCT were 100%, 85.7%, 93.5%, and 100%, respectively. Sixteen, nine, and four patients were found to have mild, moderate, and severe AR on TTE, respectively. The corresponding ROA by MDCT were 3.25 +/- 1.04 mm(2), 4.16 +/- 1.19 mm(2), and 11.30 +/- 6.13 mm(2), respectively. CONCLUSION: MDCT data acquired for the coronary artery evaluation can be used for the detection of aortic regurgitation with high diagnostic accuracy without additional scanning or radiation and can support appropriate referral for TTE. |
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Authors:
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Irfan Zeb; Yasmin S Hamirani; Songshuo Mao; Hussain Isma'eel; Anila Saeed; Sudha Karnwal; Sameer Raina; Jina Chung; Matthew J Budoff |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Academic radiology Volume: 17 ISSN: 1878-4046 ISO Abbreviation: Acad Radiol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-08-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440159 Medline TA: Acad Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 1006-11 Citation Subset: IM |
Affiliation:
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Division of Cardiology Los Angeles Biomedical Research Institute Harbor-UCLA, Torrance, CA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aortic Valve Insufficiency / radiography*, ultrasonography Female Humans Male Middle Aged Sensitivity and Specificity Tomography, X-Ray Computed / methods* |
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