Document Detail


Detecting an undiagnosed case of nonsyndromic facial dysmorphism using geometric morphometrics.
MedLine Citation:
PMID:  18798770     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Johns Hopkins University Center for Craniofacial Development and Disorders estimates that 1 in 3,000 children born in the United States is diagnosed with a rare form of craniosynostosis. Although the medical literature has documented numerous descriptions of craniofacial disorders from an anthropometric or genetic perspective, considerably fewer reports of these anomalies have been documented in the context of forensic anthropology. Similar genetic origins of many craniofacial anomalies generate ranges of phenotypic variation between and even within documented cases, producing difficulties in acquiring correct diagnoses. Identical physical characteristics manifested in different disorders create further complications in identifying a craniofacial syndrome in skeletal remains. Reported here is an unusual case of a possibly undiagnosed craniofacial abnormality in a set of identified skeletal remains from a North Carolina homicide case. Traditional metric and geometric morphometric approaches were utilized to further investigate morphological shape differences between the case study and a reference sample. Results show significant differences suggesting a nonsyndromic form of craniosynostosis.
Authors:
Sheena M Harris; Ann H Ross
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-09-16
Journal Detail:
Title:  Journal of forensic sciences     Volume:  53     ISSN:  1556-4029     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-21     Completed Date:  2009-03-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1308-12     Citation Subset:  IM    
Affiliation:
Department of Sociology and Anthropology, North Carolina State University, Campus Box 8107, Raleigh, NC 27695-8107, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Craniofacial Abnormalities / diagnosis*
Female
Forensic Anthropology / methods*
Homicide
Humans
Palate / abnormalities,  pathology
Sacrum / pathology
Skull / pathology
Spina Bifida Occulta / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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