Document Detail

Detecting bacteria in platelet concentrates by use of reagent strips.
MedLine Citation:
PMID:  12385414     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Iatrogenic infection of immunosuppressed or immunocompromised hosts secondary to receipt of blood components containing bacteria may result in serious adverse outcomes. Measurement of pH and glucose by use of inexpensive reagent strips has been proposed as a practical means of screening for bacteria in platelet concentrate (PC) units. STUDY DESIGN AND METHODS: Glucose and pH were measured in 3093 PC units by use of reagent strips (Multistix, Bayer Corp.) to screen for bacterial content. Any PC classified by the reagent strip method as containing bacteria was subsequently cultured to confirm the presence and quantity of bacteria present. RESULTS: Thirty of 3093 PC units were classified as containing bacteria by the reagent strip method. Two of the 30 PC units positive by the reagent strip method were also positive by standard bacterial culture technique. Bacillus cereus was isolated from both units. CONCLUSION: Screening PC units by the reagent strip method resulted in 9.7 units per 1000 being wasted, but prevented two patients from receiving a PC unit containing B. cereus.
J B Werch; Paulette Mhawech; C E Stager; E I Banez; Benjamin Lichtiger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Transfusion     Volume:  42     ISSN:  0041-1132     ISO Abbreviation:  Transfusion     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-10-18     Completed Date:  2002-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417360     Medline TA:  Transfusion     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1027-31     Citation Subset:  IM    
Department of Pathology, Baylor College of Medicine; and The University of Texas M. D. Anderson Cancer Center, Houston, USA.
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MeSH Terms
Bacillus cereus / isolation & purification
Bacteria / isolation & purification*
Blood Glucose / analysis
Blood Platelets / metabolism,  microbiology*
Colony Count, Microbial
Hydrogen-Ion Concentration
Reagent Strips*
Reg. No./Substance:
0/Blood Glucose; 0/Reagent Strips

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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