| Detecting pleiotropy and epistasis using variance components linkage analysis in jPAP. | |
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MedLine Citation:
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PMID: 22189468 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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jPAP (Java Pedigree Analysis Package) performs variance components linkage analysis of either quantitative or discrete traits. Multivariate linkage analysis of two or more traits (all quantitative, all discrete, or any combination) allows the inference of pleiotropy between the traits. The inclusion of multiple quantitative trait loci in linkage analysis allows the inference of epistasis between loci. A user-friendly graphical user interface facilitates the usage of jPAP. |
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Authors:
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Sandra J Hasstedt; Alun Thomas |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2011-12-23 |
Journal Detail:
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Title: Human heredity Volume: 72 ISSN: 1423-0062 ISO Abbreviation: Hum. Hered. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-12-22 Completed Date: 2012-04-17 Revised Date: 2013-02-19 |
Medline Journal Info:
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Nlm Unique ID: 0200525 Medline TA: Hum Hered Country: Switzerland |
Other Details:
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Languages: eng Pagination: 258-63 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 S. Karger AG, Basel. |
Affiliation:
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Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA. sandy@genetics.utah.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Epistasis, Genetic* Genetic Linkage* Genetic Pleiotropy* Humans Internet Models, Genetic Pedigree* Quantitative Trait, Heritable Software* |
| Grant Support | |
ID/Acronym/Agency:
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GM081417/GM/NIGMS NIH HHS; HD17463/HD/NICHD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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