| Detectability of urinary stones on virtual nonenhanced images generated at pyelographic-phase dual-energy CT. | |
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MedLine Citation:
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PMID: 20574095 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the detectability of urinary stones on virtual nonenhanced images generated at pyelographic-phase dual-energy computed tomography (CT). MATERIALS AND METHODS: This retrospective HIPAA-compliant study was institutional review board approved. All included patients had previously consented to the use of their medical records for research. Sixty-two patients (38 men, 24 women; age range, 35-91 years) had undergone CT urography, which consisted of nonenhanced and pyelographic-phase dual-energy CT performed by using a dual-source scanner. Commercial software was used to create virtual nonenhanced images by suppressing the iodine signal from the pyelographic-phase dual-energy CT scans. Two radiologists, in consensus, evaluated the virtual nonenhanced images for the presence of stones. Sensitivity for detecting stones was calculated on a per-stone basis. Sensitivity, specificity, and accuracy were also calculated on a per-renal unit (defined as the intrarenal collecting system and ureter of one kidney) basis. The true nonenhanced scan was considered the reference standard. A jackknife method was used because any patient may have multiple stones. RESULTS: Of 62 patients with 122 renal units, 21 patients with 25 renal units had a total of 43 stones (maximal transverse diameter range, 1-24 mm; median, 3 mm). The overall sensitivity for detecting stones was 63% (27 of 43 stones) per stone. Sensitivities were 29% (four of 14 stones) for 1-2-mm stones, 64% (nine of 14 stones) for 3-4-mm stones, 83% (five of six stones) for 5-6-mm stones, and 100% (nine of nine stones) for 7-mm or larger (7, 7, 7, 8, 8, 9, 11, 15, and 24 mm) stones. All three ureteral stones (3, 4, and 8 mm) were correctly identified. The sensitivity, specificity, and accuracy for detecting stones on a per-renal unit basis were 65% (17 of 26 renal units), 92% (88 of 96 renal units), and 86% (105 of 122 renal units), respectively. CONCLUSION: Virtual nonenhanced images generated at pyelographic-phase dual-energy CT enabled the detection of urinary stones with moderate accuracy. The detection of small (1-2-mm) stones was limited. |
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Authors:
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Naoki Takahashi; Terri J Vrtiska; Akira Kawashima; Robert P Hartman; Andrew N Primak; Joel G Fletcher; Cynthia H McCollough |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 256 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-24 Completed Date: 2010-07-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 184-90 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Confidence Intervals Contrast Media / diagnostic use Female Humans Iohexol / diagnostic use Male Middle Aged Radiographic Image Interpretation, Computer-Assisted Radiography, Dual-Energy Scanned Projection / methods Retrospective Studies Sensitivity and Specificity Software Subtraction Technique Tomography, X-Ray Computed / methods* Urinary Calculi / radiography* Urography |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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