Document Detail


Detailed analysis of patients with matched ventilation-perfusion defects and chest radiographic opacities.
MedLine Citation:
PMID:  8229223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed a retrospective evaluation of the data obtained from the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study to determine the prevalence and distribution of pulmonary embolism (PE) in patients with matching ventilation-perfusion (V/Q) defects and chest radiographic opacities (triple matches). From the 1,487 patients in whom diagnostic V/Q scans were obtained, 247 (17%) patients were recorded as having matching V/Q defects and chest radiograph opacities in at least one lung zone. Diagnostic angiograms were available for 275 lung zones (233 patients) which demonstrated matching V/Q defects and chest radiograph opacities. The overall prevalence of PE in all lung zones with triple matches was 26%. The prevalences of PE in the upper, middle and lower lung zones were 11%, 12% and 33%, respectively. Pulmonary embolism was significantly more common in lower lung zone triple matches compared with the upper and middle lung zone triple matches (p < 0.005). There was no correlation between the size of the V/Q and chest radiographic abnormalities and the prevalence of PE. We conclude that in patients with matching V/Q defects and chest radiographic opacities isolated to the upper and middle zones the V/Q scan can be interpreted as representing a low probability of PE. Similar findings in the lower lung zones represent an intermediate probability of PE. The application of this modification to V/Q scan interpretation criteria will aid in reducing the number of intermediate V/Q lung scan interpretations.
Authors:
D F Worsley; C K Kim; A Alavi; H I Palevsky
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  34     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1993-11-29     Completed Date:  1993-11-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1851-3     Citation Subset:  IM    
Affiliation:
Div. of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104.
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MeSH Terms
Descriptor/Qualifier:
Humans
Lung / radiography*,  radionuclide imaging
Pulmonary Artery / radiography
Pulmonary Embolism / radiography,  radionuclide imaging*
Retrospective Studies
Ventilation-Perfusion Ratio*
Grant Support
ID/Acronym/Agency:
N01-HR-34007/HR/NHLBI NIH HHS; N01-HR-34008/HR/NHLBI NIH HHS; N01-HR-34009/HR/NHLBI NIH HHS

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