Document Detail


Destructive dural ectasia of dorsal and lumbar spine with cauda equina syndrome in a patient with ankylosing spondylitis.
MedLine Citation:
PMID:  21331306     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
We present a patient with longstanding ankylosing spondylitis complicated with cauda equina syndrome. The patient suffered from increasing pain in the leg with reduced sensitivity and extremely cold feet associated with incontinence. Diagnostic workup revealed dural ectasia, arachnoiditis and a spinal inflammatory mass leading to extensive vertebral bone destruction. Of interest, this was not only found in the lumbar spine region (which is typical in cases of cauda equina syndrome associated with ankylosing spondylitis) but also in the lower cervical spine (C7) and upper dorsal spine. Moreover, the bone destructive phenotype of this complication of long-standing AS contrasts with the usual characteristics of new bone formation and ankylosis. As initial treatment with anti-inflammatory drugs was not sufficiently successful, infliximab therapy was started which resulted in manifest clinical improvement as chronic pain, incontinence and laboratory signs of inflammation progressively disappeared.
Authors:
Marijke Van Hoydonck; Kurt de Vlam; Rene Westhovens; Frank P Luyten; Rik J Lories
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Publication Detail:
Type:  Journal Article     Date:  2010-08-26
Journal Detail:
Title:  The open rheumatology journal     Volume:  4     ISSN:  1874-3129     ISO Abbreviation:  Open Rheumatol J     Publication Date:  2010  
Date Detail:
Created Date:  2011-02-18     Completed Date:  2011-07-14     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101480507     Medline TA:  Open Rheumatol J     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  31-4     Citation Subset:  -    
Affiliation:
Division of Rheumatology, University Hospitals Leuven, Herestraat 49, B-3000, Leuven, Belgium.
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