Document Detail

Desquamative inflammatory vaginitis as a manifestation of vitamin D deficiency associated with Crohn disease: case reports and review of the literature.
MedLine Citation:
PMID:  21049766     Owner:  NLM     Status:  MEDLINE    
Desquamative inflammatory vaginitis (DIV) is a chronic disorder associated with yellow vaginal discharge, vulvovaginal burning and pruritus, and dyspareunia. The cause of DIV is unknown; however, infectious, hormonal, and inflammatory etiologies have been proposed. In this series, we observe the association of DIV and vitamin D deficiency by reporting 4 cases of women with DIV and vitamin D deficiency associated with Crohn disease. We further show that the DIV symptoms resolve when the circulating concentrations of 25-hydroxyvitamin D (25-HD) returned to normal. These data provide further support for the notion that DIV can be associated with vitamin D deficiency and DIV symptoms reflect altered vaginal mucous membrane function.
Monica Peacocke; Erin Djurkinak; Hui C Tsou; Susan Thys-Jacobs
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis     Volume:  86     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-11-05     Completed Date:  2010-11-23     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  39-46     Citation Subset:  IM    
VA New York Harbor Healthcare System, New York Campus, New York, USA.
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MeSH Terms
Crohn Disease / complications*
Inflammation / etiology
Mucous Membrane / pathology
Vaginitis / etiology*,  physiopathology
Vitamin D / analogs & derivatives,  blood
Vitamin D Deficiency / complications*,  etiology
Reg. No./Substance:
1406-16-2/Vitamin D; 64719-49-9/25-hydroxyvitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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