Document Detail

Despite expression in embryonic visceral mesoderm, H2.0 is not essential for Drosophila visceral muscle morphogenesis.
MedLine Citation:
PMID:  1678322     Owner:  NLM     Status:  MEDLINE    
H2.0, a homeobox gene identified by homology to the Sex combs reduced homeobox of Drosophila, is expressed in all the cellular precursors of the visceral musculature. By analogy to the essential function of most other known homeobox genes in determining the fate of cells where they are expressed, we hypothesized that mutation of H2.0 would disrupt gut muscle development. In this paper, we show that a small deletion, which eliminates H2.0, has no detectable effect on normal gut morphogenesis, visceral muscle actin organization, or larval peristalsis.
M Barad; A Erlebacher; W McGinnis
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Developmental genetics     Volume:  12     ISSN:  0192-253X     ISO Abbreviation:  Dev. Genet.     Publication Date:  1991  
Date Detail:
Created Date:  1991-09-17     Completed Date:  1991-09-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7909963     Medline TA:  Dev Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  206-11     Citation Subset:  IM    
Department of Human Genetics, Yale University, New Haven, Connecticut 06511.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chromosome Deletion
Drosophila / embryology,  genetics*
Gene Expression
Genes, Homeobox*
Mesoderm / metabolism*
Morphogenesis / genetics
Muscles / cytology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of storage time and temperature on urinary enzymes.
Next Document:  DNA polymorphisms of apolipoprotein B and AI/CIII genes and response to gemfibrozil treatment.