| Desmoplastic trichoepithelioma. | |
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MedLine Citation:
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PMID: 20082889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Desmoplastic trichoepithelioma (DTE) is an uncommon adnexal tumor usually found on the face of young women. OBJECTIVE: We sought to describe the clinical and histologic characteristics of DTE and discuss management strategies for these tumors. METHODS: We conducted a retrospective case series and review of the literature. RESULTS: A series of 17 cases of DTE is reported. Of our patients, 82% were female and half of all these cases occurred on the cheek. Unlike previous reports, the patients in our study were slightly older, with 53% older than 51 years and 71% between the ages of 31 and 60 years at the time of surgery (mean age 49 years, median age 52 years, range 14-81 years). Approximately 38% of the tumors had been present for 1 to 2 years before presentation. The average size of the tumors at the time of surgery was 0.8 x 0.6 cm. All cases were treated with Mohs micrographic surgery. To date, none of the tumors have recurred. LIMITATIONS: This is a small case series. The referral patterns of our predominantly Mohs micrographic surgery clinic might further bias this study. CONCLUSION: DTE is a benign tumor that has a predilection for the face. With its rapid growth, aggressive histologic features that may be confused with basal cell carcinoma, and tendency to arise in cosmetically and functionally sensitive areas, these tumors should be removed in a manner that assures clear surgical margins, such as Mohs micrographic surgery. |
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Authors:
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Adam J Mamelak; Leonard H Goldberg; Tracy M Katz; Jeffery J Graves; Ofer Arnon; Arash Kimyai-Asadi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 62 ISSN: 1097-6787 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-19 Completed Date: 2010-02-18 Revised Date: 2011-02-04 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 102-6 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Methodist Hospital, Houston, Texas, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carcinoma, Basal Cell / pathology Cheek Facial Neoplasms / pathology*, surgery Female Humans Male Middle Aged Mohs Surgery Neoplasms, Adnexal and Skin Appendage / pathology*, surgery Retrospective Studies Skin Neoplasms / pathology |
| Comments/Corrections | |
Comment In:
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J Am Acad Dermatol. 2011 Feb;64(2):438-9
[PMID:
21238832
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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