Document Detail

Designing a vaccination strategy against dengue.
MedLine Citation:
PMID:  23011455     Owner:  NLM     Status:  In-Data-Review    
In this work we propose a mathematical approach to estimate the dengue force of infection, the average age of dengue first infection, the optimum age to vaccinate children against dengue in a routine fashion and the optimum age interval to introduce the dengue vaccine in a mass vaccination campaign. The model is based on previously published models for vaccination against other childhood infections, which resulted in actual vaccination programmes in Brazil. The model was applied for three areas of distinct levels of endemicity of the city of Recife in Northeastern State of Pernambuco, Brazil. Our results point to an optimal age to introduce the dengue vaccine in the routine immunization programme at two years of age and an age interval to introduce a mass vaccination between three and 14 years of age.
Marcos Amaku; Laurent Coudeville; Eduardo Massad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista do Instituto de Medicina Tropical de São Paulo     Volume:  54 Suppl 18     ISSN:  1678-9946     ISO Abbreviation:  Rev. Inst. Med. Trop. Sao Paulo     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507484     Medline TA:  Rev Inst Med Trop Sao Paulo     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  18-21     Citation Subset:  IM    
School of Veterinary Medicine, University of São Paulo, Brazil.
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