Document Detail


Design of a wireless telemetric backpack device for real-time in vivo measurement of pressure-volume loops in conscious ambulatory rats.
MedLine Citation:
PMID:  19162825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pressure - Volume (PV) analysis is the de facto standard for assessing myocardial function. Conductance based methods have been used for the past 27 years to generate instantaneous left ventricular (LV) volume signal. Our research group has developed the instrumentation and the algorithm for obtaining PV loops based on the measurement of real - time admittance magnitude and phase from the LV of anaesthetized mice and rats. In this study, the instrumentation will be integrated into an ASIC (Application Specific Integrated Circuit) and a backpack device will be designed along with this ASIC. This will enable measurement of real-time in vivo P-V loops from conscious and ambulatory rats, useful for both acute and chronic studies.
Authors:
Karthik Raghavan; Anil T G Kottam; Jonathan W Valvano; John A Pearce
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2008     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2008  
Date Detail:
Created Date:  2009-02-16     Completed Date:  2009-05-07     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  993-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / physiology*
Blood Pressure Determination / instrumentation*,  veterinary
Cardiac Catheterization / instrumentation*,  veterinary
Consciousness
Equipment Design
Equipment Failure Analysis
Monitoring, Ambulatory / instrumentation*,  veterinary
Plethysmography, Impedance / instrumentation*,  veterinary
Rats
Reproducibility of Results
Sensitivity and Specificity
Stroke Volume / physiology*
Telemetry / instrumentation*,  veterinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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