Document Detail

Design, validation, and utilization of an articular cartilage impact instrument.
MedLine Citation:
PMID:  17236518     Owner:  NLM     Status:  MEDLINE    
This paper describes the development and use of an instrument mechanically to impact bovine articular cartilage and record the event using a piezoelectric accelerometer, as well as to carry out post-impact characterization of the tissue. Two levels of impact (low: 6 cm drop height, 18.4 N tup; high: 10 cm drop height, 27.8 N tup) were chosen such that the former did not show gross damage upon inspection, while the latter showed substantial gross damage. Peak stress, time to peak stress, and impact duration were taken from data recorded by the instrument. Three cartilage biomechanical properties (aggregate modulus, Poisson's ratio, and permeability) were acquired by creep indentation, and tissue morphology rated on a standardized scale was also determined. When subjected to the high level of impact, articular cartilage showed statistically significant (p < 0.05) differences in all three impact metrics and morphology. This high level of impact also resulted in a 37 per cent decrease in the aggregate modulus of the tissue. Lower drop heights resulted in more consistent impact curves, demonstrated less standard deviation, and did not change the biomechanical properties of the tissues. With the instrument and techniques described in this study, articular cartilage can be subjected to specific levels of impact in order to study injury biomechanics of the tissue at specific levels of mechanical damage.
C C Scott; K A Athanasiou
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Publication Detail:
Type:  Evaluation Studies; In Vitro; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Validation Studies    
Journal Detail:
Title:  Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine     Volume:  220     ISSN:  0954-4119     ISO Abbreviation:  Proc Inst Mech Eng H     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2007-01-22     Completed Date:  2007-02-22     Revised Date:  2009-06-08    
Medline Journal Info:
Nlm Unique ID:  8908934     Medline TA:  Proc Inst Mech Eng H     Country:  England    
Other Details:
Languages:  eng     Pagination:  845-55     Citation Subset:  IM    
Department of Bioengineering, Rice University, 6100 Main St, Keck Hall, Suite 116, Houston, Texas 77584, USA.
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MeSH Terms
Biomechanics / instrumentation*,  methods
Cartilage, Articular / cytology*,  physiology*
Equipment Design
Equipment Failure Analysis
Hardness Tests / instrumentation*,  methods
Physical Stimulation / instrumentation*,  methods
Reproducibility of Results
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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