| Design and performance evaluation of a whole-body Ingenuity TF PET-MRI system. | |
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MedLine Citation:
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PMID: 21508443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Ingenuity TF PET-MRI is a newly released whole-body hybrid PET-MR imaging system with a Philips time-of-flight GEMINI TF PET and Achieva 3T X-series MRI system. Compared to PET-CT, modifications to the positron emission tomography (PET) gantry were made to avoid mutual system interference and deliver uncompromising performance which is equivalent to the standalone systems. The PET gantry was redesigned to introduce magnetic shielding for the photomultiplier tubes (PMTs). Stringent electromagnetic noise requirements of the MR system necessitated the removal of PET gantry electronics to be housed in the PET-MR equipment room. We report the standard NEMA measurements for the PET scanner. PET imaging and performance measurements were done at Geneva University Hospital as described in the NEMA Standards NU 2-2007 manual. The scatter fraction (SF) and noise equivalent count rate (NECR) measurements with the NEMA cylinder (20 cm diameter) were repeated for two larger cylinders (27 cm and 35 cm diameter), which better represent average and heavy patients. A NEMA/IEC torso phantom was used for overall assessment of image quality. The transverse and axial resolution near the center was 4.7 mm. Timing and energy resolution of the PET-MR system were measured to be 525 ps and 12%, respectively. The results were comparable to PET-CT systems demonstrating that the effect of design modifications required on the PET system to remove the harmful effect of the magnetic field on the PMTs was negligible. The absolute sensitivity of this scanner was 7.0 cps kBq(-1), whereas SF was 26%. NECR measurements performed with cylinders having three different diameters, and image quality measurements performed with IEC phantom yielded excellent results. The Ingenuity TF PET-MRI represents the first commercial whole-body hybrid PET-MRI system. The performance of the PET subsystem was comparable to the GEMINI TF PET-CT system using phantom and patient studies. It is conceived that advantages of hybrid PET-MRI will become more evident in the near future. |
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Authors:
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H Zaidi; N Ojha; M Morich; J Griesmer; Z Hu; P Maniawski; O Ratib; D Izquierdo-Garcia; Z A Fayad; L Shao |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. Date: 2011-04-20 |
Journal Detail:
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Title: Physics in medicine and biology Volume: 56 ISSN: 1361-6560 ISO Abbreviation: Phys Med Biol Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-27 Completed Date: 2011-08-15 Revised Date: 2012-04-26 |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 3091-106 Citation Subset: IM |
Affiliation:
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Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, Switzerland. habib.zaidi@hcuge.ch |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Equipment Design Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging / instrumentation*, standards Positron-Emission Tomography / instrumentation*, standards Scattering, Radiation Scintillation Counting Whole Body Imaging |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL071021/HL/NHLBI NIH HHS; R01 HL071021-09/HL/NHLBI NIH HHS |
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