| Design and performance evaluation of single-use whole-sterile "plug & play" kits for routine automated production of [(11)C]choline and [(11)C]methionine with radiopharmaceutical quality. | |
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MedLine Citation:
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PMID: 20685129 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We herein describe the design and performance evaluation of single-use whole-sterile "plug & play" kits for routine automated production of [(11)C]methionine and [(11)C]choline for human use. Kits were designed for maximal simplicity and ease of using modules from Eckert & Ziegler Modular Lab System. The use of all-disposable sterile medical-grade material, helps ensure safety and cGMP compliance. The quick set-up and removal ("plug & play") also reduces radiation burden to operator. |
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Authors:
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Gemma Quincoces; Luisa López-Sánchez; María Sánchez-Martínez; Macarena Rodríguez-Fraile; Iván Peñuelas |
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Publication Detail:
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Type: Journal Article Date: 2010-07-22 |
Journal Detail:
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Title: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine Volume: 68 ISSN: 1872-9800 ISO Abbreviation: Appl Radiat Isot Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-09-10 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306253 Medline TA: Appl Radiat Isot Country: England |
Other Details:
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Languages: eng Pagination: 2298-301 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Radiopharmacy Unit, Department of Nuclear Medicine, University Hospital, University of Navarra School of Medicine, Av. Pío XII 36, 31008 Pamplona, Spain. gquinfer@unav.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Automation Carbon Radioisotopes / chemistry* Choline / chemical synthesis* Methionine / chemical synthesis* Radiopharmaceuticals / chemical synthesis* |
| Chemical | |
Reg. No./Substance:
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0/Carbon Radioisotopes; 0/Radiopharmaceuticals; 62-49-7/Choline; 63-68-3/Methionine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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