| Design of a novel polymeric heart valve. | |
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MedLine Citation:
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PMID: 19995147 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polymeric heart valves could offer an optimum alternative to current prostheses, by joining the advantages of mechanical and bioprosthetic valves. Though a number of materials suitable for this application have recently become available, significant improvements in the valve design are still needed. In this paper, a novel polymeric heart valve design is proposed and its optimization procedure, based on the use of finite elements, is described. The design strategy was aimed at reducing the energy absorbed during the operating cycle, resulting in high hydrodynamic performances and reduced stress levels. The efficacy of the design strategy was assessed by comparing the valve dynamics and stress levels predicted numerically during the cycle with those of an existing and well qualified polymeric valve design. The improved hydrodynamic performance of the proposed design was confirmed experimentally, by in vitro testing in a pulse duplicator. |
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Authors:
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G Burriesci; F Cavallo Marincola; C Zervides |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of medical engineering & technology Volume: 34 ISSN: 1464-522X ISO Abbreviation: J Med Eng Technol Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-09 Completed Date: 2010-03-03 Revised Date: 2011-05-25 |
Medline Journal Info:
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Nlm Unique ID: 7702125 Medline TA: J Med Eng Technol Country: England |
Other Details:
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Languages: eng Pagination: 7-22 Citation Subset: IM |
Affiliation:
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Cardiovascular Engineering & Medical Devices Group, Department of Mechanical Engineering, UCL, Torrington Place, WC1E 7JE, London, UK. G.Burriesci@UCL.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials* Computer Simulation Equipment Design Finite Element Analysis Heart Valve Prosthesis* Materials Testing Models, Cardiovascular* Polymers / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/Polymers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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