Document Detail


Design of a novel polymeric heart valve.
MedLine Citation:
PMID:  19995147     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polymeric heart valves could offer an optimum alternative to current prostheses, by joining the advantages of mechanical and bioprosthetic valves. Though a number of materials suitable for this application have recently become available, significant improvements in the valve design are still needed. In this paper, a novel polymeric heart valve design is proposed and its optimization procedure, based on the use of finite elements, is described. The design strategy was aimed at reducing the energy absorbed during the operating cycle, resulting in high hydrodynamic performances and reduced stress levels. The efficacy of the design strategy was assessed by comparing the valve dynamics and stress levels predicted numerically during the cycle with those of an existing and well qualified polymeric valve design. The improved hydrodynamic performance of the proposed design was confirmed experimentally, by in vitro testing in a pulse duplicator.
Authors:
G Burriesci; F Cavallo Marincola; C Zervides
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of medical engineering & technology     Volume:  34     ISSN:  1464-522X     ISO Abbreviation:  J Med Eng Technol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-09     Completed Date:  2010-03-03     Revised Date:  2011-05-25    
Medline Journal Info:
Nlm Unique ID:  7702125     Medline TA:  J Med Eng Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  7-22     Citation Subset:  IM    
Affiliation:
Cardiovascular Engineering & Medical Devices Group, Department of Mechanical Engineering, UCL, Torrington Place, WC1E 7JE, London, UK. G.Burriesci@UCL.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Biocompatible Materials*
Computer Simulation
Equipment Design
Finite Element Analysis
Heart Valve Prosthesis*
Materials Testing
Models, Cardiovascular*
Polymers / therapeutic use*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Polymers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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