Document Detail


Design of a low-temperature plasma (LTP) probe with adjustable output temperature and variable beam diameter for the direct detection of organic molecules.
MedLine Citation:
PMID:  23413222     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
RATIONALE: The direct detection of organic molecules by mass spectrometry requires ionization methods which are compatible with ambient conditions. A relatively new strategy is the use of a free low-temperature plasma beam for ionization. The objective is to design a safe and adjustable plasma beam to enable optimal ionization and desorption parameters for specific molecules.
METHODS: A plasma probe based on a dielectric barrier discharge was designed, where the plasma is guided through an internal second tube. This setup permits different beam diameter settings and the control of the plasma temperature. The ionization and desorption of pure organic compounds, as well as their direct detection from roasted coffee beans, were tested.
RESULTS: The presented plasma probe provides improved safety with respect to arcing, ozone generation and electric shock, compared with conventional designs. The functionality of previously reported devices is expanded. A defined plasma diameter can be set by choosing the appropriate insert, while the input voltage controls the plasma temperature. The variation of measurement parameters enables the optimized direct detection of target compounds from roasted coffee beans, such as caffeine, guaiacol and vanillin.
CONCLUSIONS: The presented low-temperature plasma probe allows the fine-tuning of ionization and desorption parameters, according to the target molecules. Possible applications include: (1) The ambient ionization and desorption of organic compounds with different volatility and (2) The direct analysis of food products such as roasted coffee beans. Copyright © 2013 John Wiley & Sons, Ltd.
Authors:
Sandra Martínez-Jarquín; Robert Winkler
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rapid communications in mass spectrometry : RCM     Volume:  27     ISSN:  1097-0231     ISO Abbreviation:  Rapid Commun. Mass Spectrom.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802365     Medline TA:  Rapid Commun Mass Spectrom     Country:  England    
Other Details:
Languages:  eng     Pagination:  629-34     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 John Wiley & Sons, Ltd.
Affiliation:
CINVESTAV Unidad Irapuato, Department of Biotechnology and Biochemistry, Km. 9.6 Libramiento Norte Carr. Irapuato-León, 36821, Irapuato Gto., Mexico.
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