Document Detail

Design and in vitro performance of a novel bileaflet mechanical heart valve prosthesis.
MedLine Citation:
PMID:  15818549     Owner:  NLM     Status:  MEDLINE    
Design and in vitro performance of a novel bileaflet mechanical heart valve prosthesis are presented. The novel heart valve exhibits three main design characteristics: (i) The leaflets form a Venturi passage in open position. Thus, a beneficial pressure distribution is obtained and the leaflets are stabilised in opened position. (ii) The orifice inlet is nozzle-shaped. Flow is convectively accelerated and flow separation at the orifice inlet is avoided. (iii) The hinge design facilitates an additional axial movement of the leaflets and leads to a self cleaning effect and enhances washout of the hinges. The design of the leaflet hinges is of main importance for the functional reliability and durability of mechanical heart valves. After manufacturing first prototypes from titanium and polymeric materials the hydrodynamic performance was evaluated according to ISO 5840 and FDA guidelines. Hydrodynamic performance is comparable with the results of commonly available bileaflet mechanical heart valve prostheses. Initial durability tests showed suitable material couples for further long term studies.
D Medart; C Schmitz; G Rau; H Reul
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  28     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-04-08     Completed Date:  2005-07-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  256-63     Citation Subset:  IM    
Helmholtz-Institute for Biomedical Technologies at the RWTH Aachen, Aachen, Germany.
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MeSH Terms
Biocompatible Materials / therapeutic use
Heart Valve Prosthesis*
Polymers / therapeutic use
Prosthesis Design
Titanium / therapeutic use
Reg. No./Substance:
0/Biocompatible Materials; 0/Polymers; 7440-32-6/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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