Document Detail


Design of an in-dwelling cannula for convection-enhanced delivery.
MedLine Citation:
PMID:  21187114     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Failures of recent convection-enhanced delivery (CED) trials have underscored the need for improved CED cannulae. This study presents a novel in-dwelling cannula targeted for use in upcoming neuro-oncological or neurodegeneration trials. The cannula is reflux-resistant and easily integrated into clinical workflows. The cannula was evaluated in non-human primate CED studies performed with magnetic resonance imaging (MRI) to validate the effectiveness and safety of the infusion.
Authors:
Kathryn H Rosenbluth; Matthias Luz; Erich Mohr; Stephan Mittermeyer; John Bringas; Krystof S Bankiewicz
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-25
Journal Detail:
Title:  Journal of neuroscience methods     Volume:  -     ISSN:  1872-678X     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905558     Medline TA:  J Neurosci Methods     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
Affiliation:
Department of Neurosurgery, University of California San Francisco (UCSF), 1855 Folsom St, MCB226, San Francisco, CA 94103-0555, USA.
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