Document Detail

Design and analysis of group-randomized trials: a review of recent methodological developments.
MedLine Citation:
PMID:  14998806     Owner:  NLM     Status:  MEDLINE    
We review recent developments in the design and analysis of group-randomized trials (GRTs). Regarding design, we summarize developments in estimates of intraclass correlation, power analysis, matched designs, designs involving one group per condition, and designs in which individuals are randomized to receive treatments in groups. Regarding analysis, we summarize developments in marginal and conditional models, the sandwich estimator, model-based estimators, binary data, survival analysis, randomization tests, survey methods, latent variable methods and nonlinear mixed models, time series methods, global tests for multiple endpoints, mediation effects, missing data, trial reporting, and software. We encourage investigators who conduct GRTs to become familiar with these developments and to collaborate with methodologists who can strengthen the design and analysis of their trials.
David M Murray; Sherri P Varnell; Jonathan L Blitstein
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American journal of public health     Volume:  94     ISSN:  0090-0036     ISO Abbreviation:  Am J Public Health     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-04     Completed Date:  2004-04-01     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  1254074     Medline TA:  Am J Public Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  423-32     Citation Subset:  AIM; IM    
Department of Psychology, College of Arts and Sciences, University of Memphis, Memphis, TN, USA.
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MeSH Terms
Cluster Analysis*
Epidemiologic Research Design*
Intervention Studies*
Public Health Practice*
Randomized Controlled Trials as Topic / methods*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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