| Design of the Beta-Blocker Evaluation Survival Trial (BEST). The BEST Steering Committee. | |
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MedLine Citation:
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PMID: 7778543 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Central to our current understanding of heart failure is the concept that compensatory mechanisms that maintain blood pressure and perfusion ultimately contribute to worsening of ventricular function. Studies of the effect of angiotensin-converting enzyme inhibitors in patients with heart failure are consistent with this paradigm. This manuscript describes a 2,800-patient randomized trial that will definitively determine whether sympathetic nervous system antagonism with a beta blocker prolongs the life of patients with moderate to severe heart failure. |
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Authors:
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The American journal of cardiology Volume: 75 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-07-12 Completed Date: 1995-07-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1220-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Female Heart Failure / drug therapy*, mortality Humans Male Propanolamines / therapeutic use* Research Design Survival Rate |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Propanolamines; 70369-47-0/bucindolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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