| Desensitization Of Thermal Hyperemia In The Skin Is Reproductible. | |
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MedLine Citation:
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PMID: 21819479 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: Local heating increases skin blood flow SkBF (thermal hyperemia). In a previous study, we reported that a first local thermal stimulus could attenuate the hyperemic response to a second one applied later on the same skin spot, a phenomenon that we termed desensitization. However, other studies found no evidence for desensitization in similar conditions. The aim of the present work was to test whether it was related to differences in instrumentation. Methods: Twenty-eight healthy young males were studied. Two pairs of heating chambers, one custom-made (our study) and one commercial (other groups), were affixed to forearm skin. SkBF was measured with single-point laser Doppler flowmetry (LDF) (780 nm) in one pair, and laser Doppler imaging (LDI) (633 nm) in the other. A temperature step from 34 to 41°C, was applied for 30 minutes and repeated after 2 hours. Results: During the second thermal challenge, the plateau SkBF was lower than during the first thermal and was observed with each of the four combinations of SkBF measurement techniques and heating equipment (p<0.05 for all conditions, range -9 to -16% of the initial value). Conclusion: Desensitization of thermal hyperemia is not specific to peculiar operating conditions. |
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Authors:
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Johanna Frantz; Rolf Engelberger; Lucas Liaudet; Lucia Mazzolai; Bernard Waeber; François Feihl |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-8 |
Journal Detail:
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Title: Microcirculation (New York, N.Y. : 1994) Volume: - ISSN: 1549-8719 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9434935 Medline TA: Microcirculation Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 John Wiley & Sons Ltd. |
Affiliation:
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Division de Physiopathologie Clinique Service de Médecine Intensive Adulte Service d'Angiologie, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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