| Descriptive epidemiology of selected heritable birth defects in Texas. | |
| | |
MedLine Citation:
|
PMID: 22102535 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND Few population-based studies exist on descriptive epidemiologic characteristics of rare heritable birth defects. The number of birth defect cases in the Texas Birth Defects Registry (one of the largest active birth defects surveillance systems in the world) enabled us to examine six different heritable disorders (aqueductal stenosis, infantile polycystic kidney disease, achondroplasia, thanatophoric dwarfism, chondrodysplasia/dwarfism not otherwise specified (NOS), and osteogenesis imperfecta) for a variety of descriptive demographic variables. METHODS The Texas Birth Defects Registry was used to identify infants or fetuses with heritable birth defects. Crude prevalence rates were calculated and Poisson regression was used to test the association of each demographic variable (e.g., maternal age) with each of the selected genetic birth defects. RESULTS White non-Hispanics exhibited higher rates of achondroplasia and osteogenesis imperfecta than other race/ethnic groups. Lower maternal education level and to a lesser extent, paternal education level, was associated with higher rates of several disorders. The birth prevalence rate for achondroplasia decreased from 1999 through 2006. CONCLUSION The use of a large birth defects registry provides a sufficient count of cases to perform some basic epidemiologic analysis on selected rare heritable birth defects. Birth Defects Research (Part A) 2011. © 2011 Wiley-Liss, Inc. |
| | |
Authors:
|
Karen B Moffitt; Oseni O Abiri; Angela E Scheuerle; Peter H Langlois |
Related Documents
:
|
21911345 - Association of late-preterm birth with asthma in young children: practice-based study. 22012145 - Sonographic measurement of thymic size in preterm infants: prediction model for thymic ... 21920055 - Neonatal jaundice. 21775575 - Total antioxidant capacity and total oxidant status after surfactant treatment in prete... 303165 - A bleeding syndrome in infants due to acquired prothrombin complex deficiency: a survey... 16581405 - Who analysis of causes of maternal death: a systematic review. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-19 |
Journal Detail:
|
Title: Birth defects research. Part A, Clinical and molecular teratology Volume: - ISSN: 1542-0760 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101155107 Medline TA: Birth Defects Res A Clin Mol Teratol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
|
Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, Texas. Karen.Moffitt@dshs.state.tx.us. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Concise review: Inner ear stem cells--an oxymoron, but why?
Next Document: Measurement of the spiral artery jets: general principles and differences observed for small for ges...