Document Detail

A descriptive study on vitamin D levels in individuals with spinal cord injury in an acute inpatient rehabilitation setting.
MedLine Citation:
PMID:  20359685     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the prevalence of inadequate or severely deficient levels of vitamin D in patients with spinal cord injury (SCI) admitted to an inpatient rehabilitation service and to describe any associations between patient demographics and injury characteristics and vitamin D levels. DESIGN: Retrospective case series. SETTING: Academic inpatient SCI rehabilitation program. SUBJECTS: One hundred patients with SCI who were consecutively admitted to acute inpatient rehabilitation from January to December 2007. METHODS: Data were retrospectively abstracted from the patient's medical chart. OUTCOME MEASURE: VitD-25(OH). RESULTS: The prevalence of VitD-25(OH) inadequacy or severe deficiency was 93% in this sample of patients with SCI. The mean VitD-25(OH) level was 16.29 +/- 7.73 ng/mL, with a range from 7.00 to 36.80 ng/mL. Twenty-one percent of the sample had VitD-25(OH) levels that were considered as severely deficient (< or =10 ng/mL). African-American subjects had statistically significant lower mean VitD-25(OH) levels compared with Caucasian subjects (12.96 versus 17.79 ng/mL; P = .003). Persons with an incomplete injury had significant lower mean VitD-25(OH) levels compared with complete injuries (14.64 versus 18.15 ng/mL; P = .023). CONCLUSIONS: Inadequate or severely deficient levels of VitD-25(OH) were highly prevalent in patients with SCI admitted to an acute inpatient rehabilitation service. Evaluation of serum VitD-25(OH) levels are recommended in patients with SCI because low levels may contribute to osteoporosis.
Gregory A Nemunaitis; Melvin Mejia; Jennifer A Nagy; Tova Johnson; John Chae; Mary Joan Roach
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  PM & R : the journal of injury, function, and rehabilitation     Volume:  2     ISSN:  1934-1482     ISO Abbreviation:  PM R     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-02     Completed Date:  2010-06-22     Revised Date:  2010-11-10    
Medline Journal Info:
Nlm Unique ID:  101491319     Medline TA:  PM R     Country:  United States    
Other Details:
Languages:  eng     Pagination:  202-8; quiz 228     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
Department of Physical Medicine and Rehabilitation, MetroHealth Rehabilitation, Institute of Ohio, MetroHealth Medical System, Cleveland, OH, USA.
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MeSH Terms
African Americans
European Continental Ancestry Group
Inpatients / statistics & numerical data
Middle Aged
Ohio / epidemiology
Rehabilitation Centers*
Retrospective Studies
Spinal Cord Injuries / blood*,  rehabilitation
Vitamin D / analogs & derivatives*,  blood,  therapeutic use
Vitamin D Deficiency / blood,  complications*,  drug therapy,  epidemiology*
Young Adult
Grant Support
H133N060017//PHS HHS
Reg. No./Substance:
1406-16-2/Vitamin D; 64719-49-9/25-hydroxyvitamin D
Comment In:
PM R. 2010 Sep;2(9):872   [PMID:  20869689 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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