Document Detail


A descriptive study on vitamin D levels in individuals with spinal cord injury in an acute inpatient rehabilitation setting.
MedLine Citation:
PMID:  20359685     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the prevalence of inadequate or severely deficient levels of vitamin D in patients with spinal cord injury (SCI) admitted to an inpatient rehabilitation service and to describe any associations between patient demographics and injury characteristics and vitamin D levels. DESIGN: Retrospective case series. SETTING: Academic inpatient SCI rehabilitation program. SUBJECTS: One hundred patients with SCI who were consecutively admitted to acute inpatient rehabilitation from January to December 2007. METHODS: Data were retrospectively abstracted from the patient's medical chart. OUTCOME MEASURE: VitD-25(OH). RESULTS: The prevalence of VitD-25(OH) inadequacy or severe deficiency was 93% in this sample of patients with SCI. The mean VitD-25(OH) level was 16.29 +/- 7.73 ng/mL, with a range from 7.00 to 36.80 ng/mL. Twenty-one percent of the sample had VitD-25(OH) levels that were considered as severely deficient (< or =10 ng/mL). African-American subjects had statistically significant lower mean VitD-25(OH) levels compared with Caucasian subjects (12.96 versus 17.79 ng/mL; P = .003). Persons with an incomplete injury had significant lower mean VitD-25(OH) levels compared with complete injuries (14.64 versus 18.15 ng/mL; P = .023). CONCLUSIONS: Inadequate or severely deficient levels of VitD-25(OH) were highly prevalent in patients with SCI admitted to an acute inpatient rehabilitation service. Evaluation of serum VitD-25(OH) levels are recommended in patients with SCI because low levels may contribute to osteoporosis.
Authors:
Gregory A Nemunaitis; Melvin Mejia; Jennifer A Nagy; Tova Johnson; John Chae; Mary Joan Roach
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  PM & R : the journal of injury, function, and rehabilitation     Volume:  2     ISSN:  1934-1482     ISO Abbreviation:  PM R     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-02     Completed Date:  2010-06-22     Revised Date:  2010-11-10    
Medline Journal Info:
Nlm Unique ID:  101491319     Medline TA:  PM R     Country:  United States    
Other Details:
Languages:  eng     Pagination:  202-8; quiz 228     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Physical Medicine and Rehabilitation, MetroHealth Rehabilitation, Institute of Ohio, MetroHealth Medical System, Cleveland, OH, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
African Americans
European Continental Ancestry Group
Female
Humans
Inpatients / statistics & numerical data
Male
Middle Aged
Ohio / epidemiology
Prevalence
Rehabilitation Centers*
Retrospective Studies
Spinal Cord Injuries / blood*,  rehabilitation
Vitamin D / analogs & derivatives*,  blood,  therapeutic use
Vitamin D Deficiency / blood,  complications*,  drug therapy,  epidemiology*
Young Adult
Grant Support
ID/Acronym/Agency:
H133N060017//PHS HHS
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D; 64719-49-9/25-hydroxyvitamin D
Comments/Corrections
Comment In:
PM R. 2010 Sep;2(9):872   [PMID:  20869689 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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