Document Detail

Description of patients undergoing high risk angioplasty. Analyses of various databases.
MedLine Citation:
PMID:  8869016     Owner:  NLM     Status:  MEDLINE    
As the pharmacological and mechanical management of angioplasty procedures advances, the description of risk incurred during and after the procedure becomes increasingly important. A variety of measures from different sorts of databases have been devised to facilitate this task. Large public databases generally include descriptors of overall physical health and are most useful in predicting catastrophic outcomes, such as mortality. Data from smaller angiographic databases are more useful in providing specific descriptors of more common but less catastrophic events, such as abrupt closure, myocardial infarction, and emergency coronary artery bypass. Most complications are associated with abrupt closure of the vessel dilated. In modern PTCA series, the risk of serious ishcaemic complications ranges from as low as 3% to as high as 12.9%. Since the inception of angioplasty, it has been observed repeatedly that angiographic characteristics of target lesions can predict the likelihood of both success and ischaemic complications. It has also become apparent that such clinical factors as unstable angina with ST segment changes or recent myocardial infarction also play important roles by providing a thrombogenic milieu in which the risk of intravascular thrombosis is increased. Although advances in operator skills and equipment, as well as new devices have dramatically increased the degree of lesion complexity which may be approached with PTCA, the actual characteristics which are associated with abrupt closure have undergone little change.
N S Kleiman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European heart journal     Volume:  16 Suppl L     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1997-01-08     Completed Date:  1997-01-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  30-5     Citation Subset:  IM    
Section of Cardiology, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Information Systems*
Multivariate Analysis
Myocardial Infarction / therapy
Myocardial Revascularization
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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