| Description of original endoscopic findings and respiratory functional assessment using barometric whole-body plethysmography in dogs suffering from brachycephalic airway obstruction syndrome. | |
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MedLine Citation:
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PMID: 18952471 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical features of brachycephalic airway obstructive disease in 11 brachycephalic dogs are described in this study. The respiratory strategy was assessed before (n=11) and after (n=6) surgery using barometric whole-body plethysmography (BWBP), with the relationship between BWBP variables and the severity of the clinical signs assessed by the use of a respiratory score based on clinical, radiographic and endoscopic findings. Partial collapse of the left main bronchus was a common finding not previously described as part of the brachycephalic airway obstructive disease syndrome. Epiglottic cysts, laryngeal granulomas and nasopharyngeal turbinates in English Bulldogs were other previously unreported findings. No significant correlation between the respiratory score and any of the BWBP variables was detected. Compared to healthy dogs, brachycephalic dogs had a significantly lower Te/Ti ratio (expiratory time over inspiratory time), peak inspiratory flow (PIF) per kg bodyweight (BW), significantly higher peak expiratory flow (PEF) per kgBW, PEF/PIF, and enhanced pause. These variations are compatible with upper airway obstructions primarily in the extrathoracic airways. Following surgery, a significant decrease in PEF/PIF was detected. The study showed that BWBP could be used to characterise the respiratory strategy in brachycephalic dogs before and after surgery. |
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Authors:
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Fr?d?rique Bernaerts; Jes?s Talavera; J?r?me Leemans; Annick Hamaide; St?phanie Claeys; Nathalie Kirschvink; C?cile Clercx |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-10-25 |
Journal Detail:
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Title: Veterinary journal (London, England : 1997) Volume: 183 ISSN: 1532-2971 ISO Abbreviation: Vet. J. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-03-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706281 Medline TA: Vet J Country: England |
Other Details:
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Languages: eng Pagination: 95-102 Citation Subset: IM |
Copyright Information:
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Copyright 2008 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department for Clinical Sciences B44, Faculty of Veterinary Medicine, University of Li?ge, 4000 Li?ge, Belgium. fbernaerts@ulg.ac.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Airway Obstruction
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diagnosis,
pathology,
surgery,
veterinary* Airway Resistance / physiology Animals Bronchoscopy / veterinary Dog Diseases / diagnosis*, pathology, surgery Dogs Female Male Plethysmography, Whole Body / methods, standards, veterinary* Respiratory Function Tests / methods, standards, veterinary* Severity of Illness Index Syndrome Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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